Actor Rob Lowe admitted in a recent interview that he was offered the juicy part of Dr. Derek Shepherd in the hit show "Grey's Anatomy" -- but turned it down!
The part went to Patrick Dempsey who has experienced a huge revival in his lagging career. Lowe says he was devastated when "Grey's Anatomy" turned out to be the top show in the US. "(I) coulda been McDreamy!" Lowe said.
"It's an occupational hazard. It's like Brad Pitt turns down 'The Matrix' to go do 'Seven Years In Tibet'. It happens to everybody."
"The great thing is that Patrick Dempsey is so great in that part and he's such a great actor," said Lowe, who walked away from the hit show 'West Wing' and saw his career flounderfor several years.
"If I'd have done [Grey's Anatomy] I wouldn't be doing this great part and having this fun on 'Brothers And Sisters'. It all works out."


